Post-Doctoral Scientist
Nationwide Children's Hospital
My undergraduate and graduate research experience focused on molecular and cellular biology with an emphasis on cell cycle regulation and metabolism. As an undergraduate I did research with Dr. David Rivers and Dr. Rebecca Brogan at Loyola University, Maryland on the expression of heat shock proteins during the development of flesh fly larvae. As a graduate student with Dr. Ruoning Wang at the Ohio State University, my research focused on the integration of cell cycle control in G2 and metabolism. I gained a solid foundation in molecular biology and expertise in metabolic assays and flow cytometry especially concerning cell synchronization and the measuring of cell cycle progression. I developed a novel method to rapidly measure the progression of cells from G2 phase to mitosis. Approaching the end of my graduate career I taught myself the python programing language and the basics of data science. For my postdoctoral training, I am continuing to develop my abilities in data science and bioinformatics along those in molecular biology at Nationwide Children's Hospital with Dr. Emily Theisen. My current research involves determining the mechanism of action for the Lysine-specific Demethylase 1 (LSD1) inhibitor SP-2509 in Ewing Sarcoma. Over the course of this project, I have discovered that in addition to inhibiting LSD1, SP-2509 acts to inhibit the incorporation of iron sulfur clusters into nascent proteins, as well as gained experience working with high-performance computing and analyzing genomic and proteomic data.
