Session 5: Preclinical Models and Clinical Translation

Moderator(s)

• 

  Alice Soragni, PhD

  Assistant Professor
  University of California, Los Angeles
  LOS ANGELES, California, United States
• 

  Elizabeth Stewart, MD (she/her/hers)

  Associate Member, Solid Tumor Division
  St. Jude Children's Research Hospital
  Memphis, Tennessee, United States

Presentations:

• 4:45 PM – 5:45 PM PST

  PROMOTING REPLICATION STRESS IS AN ACTIONABLE THERAPEUTIC OPPORTUNITY IN CHORDOMA
  

  Author: Nindo Punturi, BSc – Chordoma Foundation

  Co-Author: Arijit Ghosh, PhD – Duke University School of Medicine

  Co-Author: Caitlin King, MS – Chordoma Foundation

  Co-Author: Wendy Leung, PhD – Massachusetts General Hospital

  Co-Author: Joan Levy, PhD – Melanoma Research Alliance

  Co-Author: Lee Zou, PhD – Duke University School of Medicine

  Co-Author: Gregory M. Cote, MD PhD – Massachusetts General Hospital

  Co-Author: Daniel M. Freed, PhD – Chordoma Foundation
• 4:45 PM – 5:45 PM PST

  ALTERNATIVE LENGTHENING OF TELOMERES IN PATIENT-DERIVED XENOGRAFT MODELS OF SOFT TISSUE SARCOMAS WITH HIGH GENOMIC INSTABILITY
  

  Author: Agnieszka Wozniak, PhD – KU Leuven

  Co-Author: Nicola Biondi, n/a – Precision Sarcoma Research Group, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg

  Co-Author: Kimberly Verbeeck, n/a – KU Leuven

  Co-Author: Priya Chudasama, PhD – German Cancer Research Center

  Co-Author: Patrick Schöffski, Prof Dr – Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, KU Leuven
• 4:45 PM – 5:45 PM PST

  A NEW CLASS OF THERAPEUTIC FOR THE TREATMENT OF SARCOMAS
  

  Author: Faith H. Barnett, MD, PhD – Resolute Science, Inc.

  Co-Author: Andre Basbaum, MBA – Resolute Science, Inc.

  Co-Author: Sean Premeau, RAC – Resolute Science, Inc.

  Co-Author: Theresa Schaub, MBA – Resolute Science, Inc.

  Co-Author: Rick Crum, BS – Resolute Science, Inc.

  Co-Author: Robert Schmidt, PhD – Resolute Science, Inc.
• 4:45 PM – 5:45 PM PST

  FUSION ONCOPROTEIN SS18::SSX MODULATES BAF CHROMATIN REMODELING TO REPROGRAM TRANSCRIPTION
  

  Author: Li Li, PhD (he/him/his) – Department of Orthopaedics, University of Utah

  Presenter: Jinxiu Li, PhD (she/her/hers) – University of Utah

  Co-Author: Kevin Jones, M.D. – Department of Orthopaedics, University of Utah
• 4:45 PM – 5:45 PM PST

  FEASIBILITY OF A HARMONIZED MULTI-SITE PRECLINICAL DRUG TESTING APPROACH BY THE PEDIATRIC RESEARCH IN ONCOLOGY XENOGRAFTING CONSORTIUM (PROXC)
  

  Author: Raven Rose, BS – Memorial Sloan Kettering Cancer Center

  Co-Author: Samantha Brosius, MA – Memorial Sloan Kettering Cancer Center

  Co-Author: Leanne C. Sayles, BS – UCSF

  Co-Author: Amy C. Gross, MS – Nationwide Cancer Center

  Co-Author: Armaan Siddiquee, n/a – Memorial Sloan Kettering Cancer Center

  Co-Author: Kristina Guillan, n/a – Memorial Sloan Kettering Cancer Center

  Co-Author: Daoqi You, n/a – Memorial Sloan Kettering Cancer Center

  Co-Author: Xinyi Wang, n/a – Memorial Sloan Kettering Cancer Center

  Co-Author: Ryan D. Roberts, MD, PhD – Nationwide Children's Hospital

  Co-Author: Alejandro Sweet-Cordero, MD – UCSF

  Co-Author: Nino Rainusso, MD – Texas Children's Hospital

  Co-Author: Brian Crompton, MD – Department of Pediatrics, Dana-Farber / Boston Children’s Cancer and Blood Disorders Center Harvard Medical School

  Co-Author: Elizabeth A. Stewart, MD (she/her/hers) – St. Jude Children's Research Hospital

  Co-Author: Jason Yustein, MD, PhD – Emory Winship Cancer Institute

  Co-Author: David Jacobson, n/a – Memorial Sloan Kettering Cancer Center

  Co-Author: Janelle Walkey, n/a – Memorial Sloan Kettering Cancer Center

  Co-Author: Mary Warren, n/a – Memorial Sloan Kettering Cancer Center

  Co-Author: Andrew Kung, MD, PhD – Memorial Sloan Kettering Cancer Center

  Co-Author: Filemon S. Dela Cruz, MD (he/him/his) – Memorial Sloan Kettering Cancer Center

  Co-Author: Andrika Thomas – Memorial Sloan Kettering Cancer Center
• 4:45 PM – 5:45 PM PST

  MODELING TUMOR HETEROGENEITY IN PEDIATRIC SARCOMA
  

  Author: Elizabeth A. Stewart, MD (she/her/hers) – St. Jude Children's Research Hospital

  Co-Author: Justina McEvoy, PhD – St. Jude Children's Research Hospital

  Co-Author: Melody Allensworth, PhD – St. Jude Children's Research Hospital

  Co-Author: Michael A. Dyer, PhD – St. Jude Children’s Research Hospital

  Co-Author: Natalie Geiger, BS – St. Jude Children's Research Hospital

  Co-Author: Asha Jacob Jannu, PhD – St. Jude Children's Research Hospital

  Co-Author: Cody Ramirez, PhD – St. Jude Children's Research Hospital

  Co-Author: Michelle Knight, BS – St. Jude Children's Research Hospital