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Session 12: Immunology

Saturday, November 16, 2024
10:30 AM – 12:00 PM PST
Location: Harbor Ballroom

Presentations:

  • 10:30 AM – 12:00 PM PST
    PEMBROLIZUMAB, RADIOTHERAPY, & SURGERY VS RADIOTHERAPY & SURGERY FOR STAGE III SOFT TISSUE SARCOMA OF THE EXTREMITY: OUTCOMES & SARCOMA IMMUNE CLASS ANALYSIS IN SU2C-SARC032 RANDOMIZED CLINICAL TRIAL

    Co-Author: Yvonne M. Mowery, MD, PhD – UPMC Hillman Cancer Center

    Co-Author: Karla V. Ballman, PhD – Mayo Clinic

    Co-Author: Angela M. Hong, MBBS, MMed, PhD – Royal Prince Alfred Hospital

    Co-Author: Scott M. Schuetze, MD – University of Michigan

    Co-Author: Andrew J. Wagner, MD PhD – Dana-Farber Cancer Institute

    Co-Author: Varun Monga, MBBS – University of California San Francisco

    Co-Author: Rachel S. Heise, MS – Weill Cornell Medicine

    Co-Author: Steven Attia, DO – Mayo Clinic

    Co-Author: Edwin Choy, MD PhD (he/him/his) – Massachusetts General Hospital

    Co-Author: Melissa A. Burgess, MD – University of Pittsburgh Medical Center

    Co-Author: Susie Bae, MBBS MSc – University of Melbourne

    Co-Author: David I. Pryor, MBBS – Princess Alexandra Hospital and Queensland University of Technology

    Co-Author: Brian A. Van Tine, MD, PhD – Washington University in St. Louis

    Co-Author: Gabriel Tinoco, MD, FACP (he/him/his) – The Ohio State University, Arthur G. James Comprehensive Cancer Center,

    Co-Author: Bartosz Chmielowski, MD PhD – UCLA

    Co-Author: Carolyn Freeman, MBBS – McGill University

    Co-Author: Alessandro Gronchi, MD, FSSO (he/him/his) – Fondazione IRCCS Istituto Nazionale dei Tumori

    Co-Author: Christian F. Meyer, MD PhD – Johns Hopkins School of Medicine

    Co-Author: Mark Dickson, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Lee Hartner, MD – Abramson Cancer Center

    Co-Author: Lara E. Davis, MD (she/her/hers) – Division of Hematology/Medical Oncology, Knight Cancer Institute, Oregon Health & Science University

    Co-Author: Benjamin C. Powers, MD (he/him/his) – University of Kansas Cancer Center

    Co-Author: Ajay Subramanian, BS – Stanford University

    Co-Author: Serey Nouth, BS – Stanford University

    Co-Author: Everett J. Moding, MD, PhD (he/him/his) – Stanford University

    Co-Author: Kent J. Weinhold, PhD – Duke Cancer Institute

    Co-Author: Matt van de Rijn, MD, PhD – Stanford University

    Co-Author: Brian E. Brigman, MD – Duke Cancer Institute

    Co-Author: Richard F. Riedel, MD – Duke Cancer Institute

    Author: David G. Kirsch, MD, PhD – Princess Margaret Cancer Centre

  • 10:30 AM – 12:00 PM PST
    PHASE I/II STUDY OF THE TGF-BETA-TRAP ENHANCED ONCOLYTIC ADENOVIRUS, ADAPT-001, WITH AND WITHOUT AN IMMUNE CHECKPOINT INHIBITOR FOR SARCOMA PATIENTS

    Author: Anthony P. Conley, MD – The University of Texas MD Anderson Cancer Center

    Co-Author: Vinod Ravi, MD, MBA – The University of Texas MD Anderson Cancer Center

    Co-Author: Christina Roland, MD, MS (she/her/hers) – The University of Texas MD Anderson Cancer Center

    Co-Author: Tony Reid, MD, PhD – EpicentRx

    Co-Author: Christopher Larson, MD, PhD – EpicentRx. UCSD.

    Co-Author: Scott Caroen, BS – EpicentRx

    Co-Author: Jeannie Williams, RN, MSN, AOCNS – EpicentRx

    Co-Author: Bryan Oronsky, MD, PhD – EpicentRx

    Co-Author: Meaghan Stirn, MBA – EpicentRx

    Co-Author: Nacer Abrouk, PhD – Clinical Trial Innovations

    Co-Author: Erica Burbano, BS – EpicentRx

    Co-Author: Lucy Boyce Kennedy, MD – Cleveland Clinic

    Co-Author: Santosh Kesari, MD, PhD – Providence Saint John's Health Center

  • 10:30 AM – 12:00 PM PST
    PHASE 1 STUDY OF INTRATUMORAL BO-112 AND NIVOLUMAB IN RESECTABLE SOFT TISSUE SARCOMA UNDERGOING HYPOFRACTIONATED PREOPERATIVE RADIOTHERAPY

    Co-Author: Jie Deng, MD PhD – UCLA

    Co-Author: Aastha Pal, MS – Stanford University

    Co-Author: Katie Campbell, PhD – UCLA

    Co-Author: Scott C. Chin, BS (he/him/his) – UCLA

    Co-Author: Sarah Kremer, BS – UCLA

    Co-Author: Mito Tariveranmoshabad, BS – UCLA

    Co-Author: Ajay Subramanian, BS – Stanford University

    Co-Author: Magdalena Matusiak, PhD – Stanford

    Co-Author: Matt van de Rijn, MD, PhD – Stanford University

    Co-Author: Vishruth Reddy, MD PhD – UCLA

    Co-Author: Carol Felix, RN – UCLA

    Co-Author: Vincent Basehart, BS – UCLA

    Co-Author: Sarah Dry, MD – UCLA

    Co-Author: Scott Nelson, MD – UCLA

    Co-Author: Bartosz Chmielowski, MD PhD – UCLA

    Co-Author: Leanne Seeger, MD – UCLA

    Co-Author: Ben Levine, MD – UCLA

    Co-Author: Kambiz Motamedi, MD – UCLA

    Co-Author: Varand Ghazikhanian, MD – UCLA

    Co-Author: Arun S. Singh, MD – University of California at Los Angeles

    Co-Author: Nicholas M. Bernthal, MD – University of California Los Angeles

    Co-Author: Joseph Crompton, MD PhD – UCLA

    Co-Author: Marisol Quintero, PhD – Highlight Therapeutics

    Co-Author: Fritz Eilber, MD – UCLA

    Co-Author: Everett J. Moding, MD, PhD (he/him/his) – Stanford University

    Author: Anusha Kalbasi, MD – Stanford University

    Co-Author: Stefano Testa, MD – Beth Israel Deaconess Medical Center

  • 10:30 AM – 12:00 PM PST
    PLANNED ANALYSIS OF THE PIVOTAL IGNYTE-ESO TRIAL OF LETE-CEL IN PATIENTS WITH SYNOVIAL SARCOMA OR MYXOID/ROUND CELL LIPOSARCOMA.

    Author: Sandra P. D'Angelo, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Andrew J.S. Furness, MD, PhD – The Royal Marsden NHS Foundation Trust

    Co-Author: Fiona Thistlethwaite, MB, BChir, PhD, MRCP – The Christie NHS Foundation Trust and University of Manchester

    Co-Author: Melissa A. Burgess, MD – University of Pittsburgh Medical Center

    Co-Author: Richard F. Riedel, MD – Duke Cancer Institute

    Co-Author: John Haanen, MD – Netherlands Cancer Institute

    Co-Author: Jonathan Noujaim, MD – Hôpital Maisonneuve-Rosemont

    Co-Author: Anna W. Chalmers, MD (she/her/hers) – Huntsman Cancer Institute, University of Utah

    Co-Author: Antonio López Pousa, MD – Hospital Santa Creu Y Sant Pau

    Co-Author: Rashmi Chugh, MD – University of Michigan Rogel Comprehensive Cancer Center

    Co-Author: Lara E. Davis, MD (she/her/hers) – Division of Hematology/Medical Oncology, Knight Cancer Institute, Oregon Health & Science University

    Co-Author: Edouard Forcade, MD, PhD – Centre Hospitalier Universitaire de Bordeaux – Hôpital Haut-Lévêque

    Co-Author: Mark Agulnik, MD – City of Hope

    Co-Author: Andrew Poklepovic, MD – School of Medicine, Virginia Commonwealth University

    Co-Author: Maria Pilar Sancho Marquez, MD – Hospital Universitario Virgen del Rocio

    Co-Author: Armando Santoro, MD – Cancer Center at Humanitas Research Hospital

    Co-Author: Silvia Stacchiotti, MD – Fondazione IRCCS Istituto Nazionale dei Tumori

    Co-Author: Sandra J. Strauss, FRCP – UCL Cancer Institute, University College London NHS Foundation Trust

    Co-Author: Brian A. Van Tine, MD, PhD – Washington University in St. Louis

    Co-Author: Kristen N. Ganjoo, MD – Stanford Comprehensive Cancer Center

    Co-Author: David A. Liebner, MD – The Ohio State University Comprehensive Cancer Center

    Co-Author: Kavya Kazipeta, MSc – Adaptimmune

    Co-Author: Dennis Williams, PharmD – Adaptimmune

    Co-Author: Mary A. Woessner, PhD – GlaxoSmithKline

    Co-Author: Thomas Faitg, PhD – GlaxoSmithKline

    Co-Author: Beth Ireland, MSc – Adaptimmune

    Co-Author: Michael J. Nathenson, MD (he/him/his) – Adaptimmune

    Co-Author: Elliot Norry, MD – Adaptimmune

    Co-Author: Albiruni Abdul Razak, MB BCh, BAO, LRCP & SI – Toronto Sarcoma Program, Princess Margaret Cancer Center

  • 10:30 AM – 12:00 PM PST
    BREAKING HLA RESTRICTION TO THERAPEUTICALLY TARGET A FUSION-DERIVED PUBLIC NEOANTIGEN IN DESMOPLASTIC SMALL ROUND CELL TUMOR

    Author: Lauren Banks, MD, PhD (she/her/hers) – Memorial Sloan Kettering Cancer Center

    Co-Author: Hannah Arkin, n/a – Memorial Sloan Kettering Cancer Center

    Co-Author: Smita Chandran, Ph.D. – Memorial Sloan Kettering Cancer Center

    Co-Author: Emily K. Slotkin, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Madelyn Espinosa-Cotton, PhD – Memorial Sloan Kettering Cancer Center

    Co-Author: Neerav Shukla, M.D. – Memorial Sloan Kettering Cancer Center

    Co-Author: Luc Morris, M.D. – Memorial Sloan Kettering Cancer Center

    Co-Author: Marc Ladanyi, M.D. – Memorial Sloan Kettering Cancer Center

    Co-Author: Andrew Kung, MD, PhD – Memorial Sloan Kettering Cancer Center

    Co-Author: Martin Klatt, M.D. – Charité University Medicine

    Co-Author: Christopher Klebanoff, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Dylan Domenico – Memorial Sloan Kettering Cancer Center

    Co-Author: Elli Papaemmanouil – Memorial Sloan Kettering Cancer Center

    Co-Author: Gunes Gundem – Memorial Sloan Kettering Cancer Center

  • 10:30 AM – 12:00 PM PST
    TRANSLATIONAL ANALYSES REVEAL MECHANISMS OF AFAMI-CEL'S ANTI-TUMOR ACTIVITY IN SYNOVIAL SARCOMA

    Co-Author: Christopher D. Dupont, PhD – Adaptimmune

    Co-Author: Natalie Bath, MSc – Adaptimmune

    Co-Author: Robyn Broad, PhD – Adaptimmune

    Co-Author: Megan Butler, n/a – Adaptimmune

    Co-Author: Chris Evans, PhD – Adaptimmune

    Co-Author: Alasdair Gunn, DPhil – Adaptimmune

    Co-Author: Martin Isabelle, PhD – Adaptimmune

    Co-Author: Ashley Liddle, MS – Adaptimmune

    Co-Author: Revashnee Naidoo, MRes – Adaptimmune

    Co-Author: Bhavna Paratala, PhD – Adaptimmune

    Co-Author: Stavros Rafail, PhD – Adaptimmune

    Co-Author: Alicia Soria, PhD – Adaptimmune

    Co-Author: Alex Tipping, PhD – Adaptimmune

    Author: Mihaela Druta, MD – Moffitt Cancer Center & Research Institute

  • 10:30 AM – 12:00 PM PST
    CELLSARCTX: A SINGLE-CELL TRANSCRIPTOMICS ATLAS OF ADOPTIVE CELLULAR THERAPY TARGETS IN SOFT TISSUE SARCOMAS

    Author: Stefano Testa, MD (he/him/his) – Beth Israel Deaconess Medical Center

    Co-Author: Aastha Pal, MS – Stanford University

    Co-Author: Ajay Subramanian, BS – Stanford University

    Co-Author: Minggui Pan, MD, PhD – Stanford University School of Medicine

    Co-Author: Nam Quoc Bui, MD – Division of Oncology, Department of Medicine, Stanford University

    Co-Author: Sushama Varma, BS – Stanford University

    Co-Author: Matt van de Rijn, MD, PhD – Stanford University

    Co-Author: Kristen N. Ganjoo, MD – Stanford Comprehensive Cancer Center

    Co-Author: Anusha Kalbasi, MD – Stanford University

    Co-Author: Everett J. Moding, MD, PhD (he/him/his) – Stanford University

  • 10:30 AM – 12:00 PM PST
    IMMUNE CORRELATES OF RESPONSE TO COMBINATION AXITINIB PLUS PEMBROLIZUMAB IN PATIENTS WITH ADVANCED SOFT TISSUE SARCOMAS INCLUDING ALVEOLAR SOFT PART SARCOMA

    Author: Breelyn A. Wilky, MD (she/her/hers) – University of Colorado School of Medicine

    Co-Author: Despina Kolonias, n/a – University of Miami School of Medicine

    Co-Author: Eric Wieder, PhD – University of Miami School of Medicine

    Co-Author: Junxiao Hu, PhD – University of Colorado School of Medicine

    Co-Author: Yonghua Zhuang, PhD – University of Colorado School of Medicine

    Co-Author: Andrew E. Rosenberg, MD – University of Miami School of Medicine

    Co-Author: Michael R. Clay, MD – University of Colorado School of Medicine

    Co-Author: Matteo Trucco, MD – Cleveland Clinic

    Co-Author: Jonathan Trent, MD, PhD – Sylvester Comprehensive Cancer Center, University of Miami Health System

    Co-Author: Krishna Komanduri, MD – University of Miami School of Medicine

    Co-Author: Eduardo Davila, PhD – University of Colorado School of Medicine

  • 10:30 AM – 12:00 PM PST
    PERIPHERAL BLOOD T CELL PHENOTYPE AND TUMOR MICROENVIRONMENT SUBTYPE ARE INDEPENDENTLY ASSOCIATED WITH IMMUNE CHECKPOINT BLOCKADE OUTCOMES IN SARCOMAS

    Author: Evan Rosenbaum, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Fiona Ehrich, MS – Memorial Sloan Kettering Cancer Center

    Co-Author: Martina Bradic, PhD – Memorial Sloan Kettering Cancer Center

    Co-Author: Mathew Adamow, n/a – Memorial Sloan Kettering Cancer Center

    Co-Author: Allison Reiner, MA – Memorial Sloan Kettering Cancer Center

    Co-Author: Ciara Kelly, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Sujana Movva, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Viswatej Avutu, MD (he/him/his) – Memorial Sloan Kettering Cancer Center

    Co-Author: Jason Chan, MD, PhD – Memorial Sloan Kettering Cancer Center

    Co-Author: Ping Chi, MD, PhD – Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine

    Co-Author: Lauren Banks, MD, PhD (she/her/hers) – Memorial Sloan Kettering Cancer Center

    Co-Author: Mark Dickson, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Mary Lou Keohan, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Mrinal Gounder, MD – Memorial Sloan Kettering Cancer Center; Weill Cornell Medical College

    Co-Author: Damon Reed, MD – Memorial Sloan Kettering

    Co-Author: Rhoena Desir, n/a – Memorial Sloan Kettering Cancer Center

    Co-Author: Cristina R. Antonescu, MD – Memorial Sloan Kettering Cancer Center

    Co-Author: Samuel Singer, MD, FACS – Memorial Sloan Kettering Cancer Center

    Co-Author: Wong Philip, PhD – Memorial Sloan Kettering Cancer Center

    Co-Author: Margaret Callahan, MD, PhD – University of Connecticut

    Co-Author: Katherine Panageas, PhD – Memorial Sloan Kettering Cancer Center

    Co-Author: William D. Tap, MD – Department of Medicine, Memorial Sloan Kettering Cancer Center Department of Medicine, Weill Cornell Medical College

    Co-Author: Ronglai Shen, PhD – Memorial Sloan Kettering Cancer Center

    Co-Author: Sandra P. D'Angelo, MD – Memorial Sloan Kettering Cancer Center