Session 2: Complex Karyotype Sarcomas

Moderator(s)

• 

  Judith Bovee

  Prof. Dr.
  LUMC
  Leiden, Zuid-Holland, Netherlands
• 

  Rebecca Gladdy, MD, PhD

  Associate Professor
  Department of Surgery, Mount Sinai Hospital; Department of Surgery, University of Toronto; Department of Surgical Oncology, Princess Margaret Cancer Centre, University of Toronto; CanSaRCC, Princess Margaret Cancer Centre, Toronto
  Toronto, Quebec, Canada

Presentations:

• 10:15 AM – 12:00 PM PST

  Keynote: Utilizing Mutational Patterns And AI For Cancer Diagnosis and Prevention
  

  Keynote Speaker: Ludmil Alexandrov, PhD – University of California San Diego
• 10:15 AM – 12:00 PM PST

  FOCAL ADHESION KINASE (FAK) IS A THERPEUTIC TARGET IN CHROMOSOME 8 GAIN-ASSOCIATED MALIGNANT PERIPHERAL NERVE SHEATH TUMORS (MPNST)
  

  Author: Guangfeng Wang, PhD – Washington University in St. Louis School of Medicine

  Co-Author: Dana C. Borcherding, PhD – Washington University in St. Louis School of Medicine

  Co-Author: xiaochun Zhang, MD – Washington University in St. Louis School of Medicine

  Co-Author: liuzhan Yang, PhD – Washington University in St. Louis School of Medicine

  Co-Author: Gorkem Oztosun, MD – Washington University in St. Louis School of Medicine, Division of Oncology

  Co-Author: Angela C. Hirbe, MD, PhD (she/her/hers) – Washington University in St. Louis School of Medicine, Division of Oncology
• 10:15 AM – 12:00 PM PST

  HISTONE DEACETYLASE-3 PLAYS A ROLE IN THE METASTATIC POTENTIAL OF A SUBPOPULATION OF CELLS IN UNDIFFERENTIATED PLEOMORPHIC SARCOMA
  

  Author: Asjah L. Wallace, B.S (she/her/hers) – Duke University

  Co-Author: Joy Ban, Ph.D. – Duke University

  Co-Author: Vijitha Puviidran, Lab Research Analyst Senior – Duke University

  Co-Author: Puvi Nadesan, Lab Research Analyst II – Duke University

  Co-Author: Eijiro Shimada, MD, PhD (he/him/his) – Duke University

  Co-Author: Nicholas Guardino, Ph.D. Student – Duke University

  Co-Author: David G. Kirsch, MD, PhD – Princess Margaret Cancer Centre

  Co-Author: Benjamin Alman, M.D. – Duke University
• 10:15 AM – 12:00 PM PST

  CDK4 IS CO-AMPLIFIED WITH EITHER TP53 PROMOTER GENE FUSIONS OR MDM2 THROUGH DISTINCT MECHANISMS IN OSTEOSARCOMA
  

  Author: Karim H. Saba, PhD (he/him/his) – Lund University

  Co-Author: Valeria Difilippo, Post-Doc – Lund University

  Co-Author: Emelie Styring, MD – Skåne University Hospital

  Co-Author: Jenny Nilsson, N/A, BSc – Lund University

  Co-Author: Linda Magnusson, N/A, MSc – Lund University

  Co-Author: Hilda van den Bos, PhD – University Medical Centre Groningen

  Co-Author: Diana C. J. Spierings, PhD – University Medical Centre Groningen

  Co-Author: Floris Foijer, PhD – University Medical Centre Groningen

  Co-Author: Michaela Nathrath, MD – Klinikum Kassel

  Co-Author: Felix Haglund de Flon, MD – Karolinska University Hospital

  Co-Author: Daniel Baumhoer, MD – University Hospital Basel

  Co-Author: Karolin Hansén Nord, PhD – Lund University
• 10:15 AM – 12:00 PM PST

  HDAC INHIBITORS DOWNREGULATE THE EXPRESSION LEVELS OF THE MINI-CHROMOSOME MAINTENANCE PROTEINS, AND INHIBIT DNA REPLICATION, IN EWING SARCOMA CELLS
  

  Author: David Gordon, MD, PhD – University of Iowa

  Co-Author: Stacia Koppenhafer, BS – University of Iowa

  Co-Author: Elizabeth Geary, BS – University of Iowa